Drug Dosage Standardization

Normalize drug rates to standard dosage units per HCPCS drug code using ASP reference.

Walkthrough

J0135 (Adalimumab) — vial size mismatch

Input: Hospital reports "\$500 per vial" for J0135 (Adalimumab). The vial is 40mg, but ASP prices per 20mg.

Method 1 — Parsed Quantity: Parse "40 MG" from the description. Formula: (\$500 / 40mg) × 20mg = \$250

Method 2 — NDC-based: NDC crosswalk says strength = 40mg. Formula: (\$500 / 40) × scaling × 20 = \$250

Method 3 — Drug Unit: drug_unit_of_measurement = 40. Formula: (\$500 / 40) × scaling × 20 = \$250

All 3 methods converge on $250. Method preference: Method 1 > Method 2 > Method 3. The best available method's result is used in accuracy scoring.

Output Columns

Three methods × dollar and percentage variants × per contract_methodology produce multiple standardized drug columns. Each method has its own output column so accuracy scoring can compare them.

ASP validation

Drug rates outside 200%–2,200% of the ASP payment limit are flagged as outliers in accuracy scoring. This catches common unit-of-measure errors — for example, a hospital that accidentally prices per mg instead of per vial, producing a rate 40× too high or too low.